Laredo is a city in Grundy County, Missouri, United States. The population was 156 at the 2020 census. Laredo is pronounced "la-read-oh" whic…Laredo is a city in Grundy County, Missouri, United States. The population was 156 at the 2020 census. Laredo is pronounced "la-read-oh" which varies from the traditional pronunciation. Laredo is located at the intersection of Missouri routes E and V approximately eight miles southeast of Trenton. Medicine Creek flows past the east side of the community.