Lynchburg is a census-designated place in DeSoto County, Mississippi, United States. The population was 2,437 at the 2010 census. Lynchburg is bordered to the east by the city of Horn Lake. According to the United States Census Bureau, the Lynchburg CDP has a total area of 2.0 square miles, of which 1.9 square miles is land and 0.04 square miles, or 1.8…Lynchburg is a census-designated place in DeSoto County, Mississippi, United States. The population was 2,437 at the 2010 census. Lynchburg is bordered to the east by the city of Horn Lake. According to the United States Census Bureau, the Lynchburg CDP has a total area of 2.0 square miles, of which 1.9 square miles is land and 0.04 square miles, or 1.80%, is water. The area of the CDP decreased from 3.5 square miles at the 2000 census due to annexation of the eastern part of the CDP by the city of Horn Lake.