Four teams enter Week 18 with a chance at locking up the first pick in the 2025 NFL Draft. Here is how each team can clinch the top spot

If the Panthers happen to win on Sunday, they would move down in the draft order. They currently pick sixth, but they cannot fall further than ninth overall. The Saints are the on

FILE - Colorado head coach Deion Sanders, left, talks with quarterback Shedeur Sanders (2) during a timeout in the second half of an NCAA college football game against Central Florida, Saturday, Sept. 28, 2024, in Orlando, Fla. AP They don’t want to lose their Week 18 game against the Eagles. They don’t care about the draft implications.

They’ll have a chance to secure a franchise-altering draft haul if they lose to the Buffalo Bills in Week 18. If the season ended today, the Patriots would own the No. 1 overall pick of the 2025 NFL draft. A loss would help them secure the pick, but a win over the Bills on Sunday could ruin their draft position.

The Giants' odds of securing the No. 1 overall pick are slim, but they still have a great chance of landing a pick inside the top three.

With the NFL season nearly complete, here are the odds for each of college football's top prospects to go first overall.

While some teams still try to make the playoffs, several NFL franchises could change their fortunes with a loss in Week 18, with the right to earn the No. 1 overall pick in the 2025 NFL Draft still up for grabs.