p40 is a relatively unknown antibody that recognizes ΔNp63-a p63 isoform and was found to be highly specific for squamous/basal cells. A large retrospective study compared the standard p63 antibody ...

ΔNp63, but not TAp63, is the principal isoform involved. Loss of p63 can affect reprogramming via several mechanisms such as reduced expression of mesenchymal–epithelial transition and ...

Accordingly, ectopic expression of TAp63 induced in vivo stratification of single-layered lung epithelia 8 and ΔNp63 induced epidermal commitment of embryonic stem cells. 9, 10 This major ...

The TP63 gene, an important member of the TP53 family, contains two independent promoters that drive the transcription of TAp63 and ΔNp63, respectively. Through alternative splicing, TAp63 and ...