Nowadays, the prevalence of sedentary lifestyles and high-caloric diets leads to an imbalance between energy intake and ...

ATP binding to the amino (N) domain and its subsequent hydrolysis by HSP90 drive a conformational ... mechanism of tumour escape from tyrosine kinase inhibitors. Derivatives of the coumarin ...

Abnormal kinase signaling can promote other harmful traits, such as neuroinflammation and neuronal cell death. On the other ...

Researchers from the Laboratory of Systems Biology, Department of Cybernetics at Tallinn University of Technology (TalTech), Estonia, recently found that the extent of AMPK activation is not the same ...