Role of the RAAS in the Pathophysiology of Heart Failure ACE inhibitors have no effect on angiotensin II formed by alternate pathways. In contrast, ARBs would be expected to inhibit the biologic ...

These agents include angiotensin-converting-enzyme (ACE) inhibitors, angiotensin-receptor blockers (ARBs), mineralocorticoid-receptor antagonists, and direct renin inhibitors, all of which can ...

However, at doses achieving the same blood pressure, RAAS inhibitors, such as angiotensin-converting-enzyme (ACE) inhibitors and ARBs, reduce proteinuria further than non-RAAS-inhibiting drugs, an ...

In the setting of ACE inhibitor-related hypotension, circumstances have evolved in such a way that peripheral resistance (and thereby BP) is dependent on angiotensin-II. As angiotensin-II is ...