Investigating how mutations in tumors alter DNA’s 3D structure—and subsequently, regulatory sequences called enhancers—can ...

Nature Neuroscience - Histone deacetylase 9 couples neuronal activity to muscle chromatin acetylation and gene expression Skip to main content Thank you for visiting nature.com.

More information: Yuri Atsumi et al, Repetitive CREB-DNA interactions at gene loci predetermined by CBP induce activity-dependent gene expression in human cortical neurons, Cell Reports (2023 ...

Researchers from Osaka University find that neuronal activity induces gene expression at the preprepared histone acetylation sites in the nucleus by influencing transcription factors and chromatin ...

The levels of H3K9 acetylation were examined at salt responsive gene promoter regions. ... FVE/HDA13 complex acts at H3K9 for deacetylation, leading to low levels of gene expression.

Gene expression can be regulated by various cellular processes with the aim to control the amount and ... and acetylation - these can help in regulating expression of the gene and offering vast ...

All the latest science news on histone acetylation from Phys.org. Find the latest news, advancements, and breakthroughs. Topics. ... Researchers uncover how instructions for gene expression are ...

In a 2011 study by Loukia G Tsaprouni et al., the association of lysine acetylation with inflammatory gene regulation (which has implications for the study of inflammatory bowel diseases such as ...

By controlling gene expression, the epigenome is largely responsible for regulating cellular differentiation and the specialized phenotype and function of cells. 3 Many epigenetic modifications are ...

The processes, DNA methylation and histone acetylation, both govern gene expression and can amplify or dampen the effects of particular genes. The team determined that early in life, ...

More information: Aishwarya Iyer-Bierhoff et al, Acetylation-induced proteasomal degradation of the activated glucocorticoid receptor limits hormonal signaling, iScience (2024). DOI: 10.1016/j ...