ESPN’s Adam Schefter pondered the possibility that the Detroit Lions could rest their starters Monday night against the San ...

San Francisco 49ers running back Isaac Guerendo, sidelined for last Sunday's game against the Miami Dolphins due to hamstring ...

Kyle Shanahan and John Lynch will be back with the San Francisco 49ers next year after a disappointing 2024 season, according ...

As the 49ers look to play spoiler against the Lions on Monday Night Football, RB Isaac Guerendo got a positive injury update.

Here’s what’s being said nationally after the Lions’ 14th win of the season. The Lions beat the 49ers 40-34 in a tuneup for Week 18 division showdown – The Associated Press Lions-49ers: Detroit ...

After losing RBs Christian McCaffrey, Jordan Mason and Elijah Mitchell to season-ending injuries, it now looks as if the ...

The San Francisco 49ers are preparing for their Week 17 contest against the Detroit Lions on Monday at Levi's Stadium in ...

San Francisco 49ers head coach Kyle Shanahan and general manager John Lynch are "not going anywhere," according to team owner ...

After losing RBs Christian McCaffrey, Jordan Mason and Elijah Mitchell to season-ending injuries, it now looks as if the ...

Trent Williams' season has come to an end. San Francisco 49ers head coach Kyle Shanahan announced that the star left tackle ...

San Francisco 49ers running back Isaac Guerendo is expected to return from foot and hamstring injuries and play Monday, a ...

After missing San Francisco's Week 16 loss to the Miami Dolphins, 49ers rookie running back Isaac Guerendo reportedly is ...