This expansion is not due to the formation of new fat cells, a process known as adipogenesis, but mostly through the ...

This 5-HT, in turn, promotes adipogenesis within white adipose tissue. Consequently, the loss of CD44 disrupts this pathway, repressing adipogenesis and thereby protecting mice from high-fat diet ...

Obesity is a significant risk factor for various metabolic diseases and, in many cases, causes ectopic fat accumulation (i.e.

Inhibition of Fat Cell Formation (Adipogenesis) – GDNF suppressed key genes involved in fat storage, including PPAR-γ, FASN, and SREBF1, while promoting fat oxidation pathways. Improved Insulin ...

Now, Cui et al. report that adipogenesis is impaired in cancer cachexia via tumour-secreted macrophage migration inhibitory factor (MIF) signalling. Inhibiting MIF alleviated cachexia in mouse ...