9 In addition, stimulation with adiponectin induces receptor activator of NFκB ligand (RANKL) and downregulates osteoprotegerin synthesis in cultured human osteoblasts, shifting the balance to ...

Here we have shown potent effects of ADP in the brain, based on the following findings: (i) ADP was increased in the CSF after i.v. injection, suggesting serum-to-CSF transport; (ii) i.c.v. ADP ...

Data from patients across 3 different randomized controlled trials showed improvements in both adiponectin and PRO-C3, primary end points in the trials.