Pancreatic cancer, one of the deadliest types of the disease, has been linked to obesity and higher stress levels, a new UCLA ...

The binding of adrenaline to an adrenergic receptor initiates a cascade of reactions inside the cell. The signal transduction cascade begins when adenylyl cyclase, a membrane- bound enzyme ...

In this study, researchers first revealed that α 2A -adrenergic receptor (ADRA2A) is a highly expressed G-protein-coupled ...

The crystal structure of a second G protein–coupled receptor sheds light on these key pharmaceutical targets. In contrast, β2AR and essentially all of the other GPCRs are present at very low ...

Pounding heart, tight muscles, and rapid breathing are all familiar effects of the “fight or flight” response. Adrenaline receptors turn on protein kinase A (PKA), which opens calcium channels in ...

Vanda Pharmaceuticals Inc. (Vanda) (NASDAQ: VNDA) today announced that a New Drug Application (NDA) was submitted to the U.S.

Since β-adrenergic receptors play a crucial role in stress-related cancer growth, commonly used beta-blockers, which are drugs prescribed for high blood pressure, could be repurposed to help ...