The Cu(I)-catalyzed cycloaddition reaction between an alkyne group and an azide group, better known as 'click chemistry,' has proven its utility in a multitude of applications in biology. Because ...

Another project involves production of cyclic alkynes via the Nicholas reaction for use in click chemistry applications. One newer project involves a collaboration with Steve Williams's molecular ...

Medicinal chemistry deals with the design ... This unique chemical signature, coupled with the small size of alkyne moieties, presents these tags as useful imaging alternatives to bulky ...