Management of a patient allergic to allopurinol can be considered a therapeutic challenge. This article highlights the diversity of medications that can be used to manage hyperuricemia during this ...

Results of a prospective, randomized, controlled trial indicate that allopurinol lowers serum uric acid levels and reduces the rate of renal degeneration in patients with mild to moderate chronic ...

Febuxostat 40 mg daily appears to be as efficacious as allopurinol in lowering serum uric acid levels. [38] Both febuxostat 40 and 80 mg can be given to patients with mild-to-moderate renal impair ...