Each protein or peptide consists of a linear sequence of amino acids. The protein primary structure conventionally begins at the amino-terminal (N) end and continues until the carboxyl-terminal (C ...

The building blocks of proteins are amino acids, which are small organic molecules that consist of an alpha (central) carbon atom linked to an amino group, a carboxyl group, a hydrogen atom, and a ...

In addition to the amino-terminal domain, TDP-43 contains two RNA-binding motifs and a glycine-rich carboxyl terminus. The majority of disease-linked mutations cluster in the carboxyl end, so ...

This pH produces the carboxyl buffer zone. If the pH s increased to that of the pK a of the amino group (9.60), another buffer is produced where there is an equilibration between the protonated ...

MANY methods have already been described for the selective degradation of peptides from the carboxyl end 1. However, the several chemical steps involved in those procedures do not allow their ...

As an endopeptidase that catalyzes the hydrolysis of protein peptide bonds, its realization form is mainly for the cleavage of the peptide bond formed by the carboxyl end of the aromatic amino ...