In Figure 2A & B, the patient serum is negative for anti-MHC class I and class II antibodies, respectively. By contrast, Figure 2C & D illustrate patient sera that are positive for both anti-MHC ...
The second ADC, SGN-CD19A (Seattle Genetics), comprises a humanized anti-CD19 monoclonal antibody conjugated with MMAF using the noncleavable MC, which is the same linker–cytotoxic agent ...
A novel mouse model offers definitive evidence that a single inhibitory receptor family governs the critical natural killer cell functions of licensing and missing-self.
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