In A-fib patients selected using established dose-reduction criteria, the 2.5-mg twice daily dose of apixaban (Eliquis; Bristol-Myers Squibb) provides protection against stroke and death versus ...

DURHAM, NC — A secondary analysis of the ARISTOTLE trial supports using the standard 5-mg twice-daily dose of apixaban (Eliquis, Bristol-Myers Squibb) in patients with atrial fibrillation (AF ...

Although international guidelines suggest that anticoagulant ... "We can say that lower-dose apixaban is both effective and safer than the full dose," Mahé said. Bonnie Ky, MD, professor of ...

The trial was conducted according to the Good Clinical Practice guidelines of the International ... assigned in a 1:1 ratio to a reduced-dose regimen of apixaban (2.5 mg twice daily) or a full ...

In the ARISTOTLE trial of apixaban versus warfarin for stroke prevention in patients with atrial fibrillation, those with two or more dose-reduction criteria (aged ≥80 years, weight ≤60 kg ...

The guidelines on extending anticoagulant treatment ... API-CAT establishes reduced-dose apixaban "as an appropriate regimen" for anticoagulation beyond the first 6 months in patients with cancer ...

Discover comprehensive details about Apixaban, including its pronunciation, uses, dosage instructions, indications, and guidelines on how and when to take it or avoid it. The updated prescription ...

We think that our result will result in a change in the guidelines and result in the use of the reduced-dose apixaban for our patients under extended treatment.” During a discussion after the ...

The study was designed and supervised by the ADVANCE (Apixaban Dose Orally vs ... The definition of major bleeding was adapted from the criteria of the International Society on Thrombosis and ...