PHILADELPHIA-- Human brain organoids are remarkable platforms for modeling features of human brain development and diseases. Building on methods to generate organoids to model different brain regions ...
Vigorous exercise can suppress appetite. People who exercise to lose weight may see this as a benefit, while others who undergo intense daily training and struggle to keep weight up and glycogen ...
Your body maintains a biological “set point” for weight, beyond calories, through powerful hormonal and neural feedback loops ...
Summary: A new study reveals that the brain uses two distinct neural pathways to regulate sugar and fat intake. In mice, glucoprivation—a drop in blood sugar levels—activates separate circuits in the ...
Obesity has increased rapidly in recent decades to affect more than 2 billion people, making it one of the largest contributors to poor health worldwide. Despite decades of research on diet and ...
Hypothalamic tanycytes generate acute hyperphagia through activation of the arcuate neuronal network
Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, No. 25 (June 23, 2020), pp. 14473-14481 (9 pages) Hypothalamic tanycytes are chemosensitive glial cells that ...
Epigenetic events, such as methylation, during early brain development in mice occur in genomic regions associated with BMI in humans, according to a new study. Once it’s cleaved, the protein ...
Ghrelin is a recently identified growth hormone (GH) secretogogue whose administration not only induces GH release but also stimulates food intake, increases adiposity, and reduces fat utilization in ...
A team of researchers reports that molecular mechanisms of brain development during early life are likely a major determinant of obesity risk. Obesity has increased rapidly in recent decades to affect ...
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