These findings offer the promise of new treatments. By disrupting arginine metabolism, the researchers successfully restored CD8 + T cell activity and slowed tumor growth in preclinical models.

Although arginine is essential for healthy immune function, cancer cells weaponize it to reprogram nearby tumor-associated macrophages (TAMs), a type of immune cell. Once reprogrammed, these TAMs ...

A team of Chinese scientists has uncovered a key mechanism behind how breast cancer cells weaponise the amino acid arginine to evade the immune system and multiply. Their findings could open up a new ...

This important study shows that nutrient stress emanating from the microenvironment induces metabolic vulnerabilities in pancreatic ductal adenocarcinoma (PDAC). Using a combination of cell-based and ...

A team of Chinese scientists has uncovered a key mechanism behind how breast cancer cells weaponise the amino acid arginine to evade the immune system and multiply. Their findings could open up a ...