The renin-angiotensin system (RAS) is considered to be the major regulator of blood pressure, electrolyte balance and renal, neuronal as well as endocrine functions related to cardiovascular control.

The blocked receptors involve AT1 receptors in the kidneys, heart, and blood vessels. Consequences of blocking the receptors include reduced blood pressure and prevention of damage to the kidneys ...

On the other hand, the randomised evaluation of strategies of left ventricular dysfunction (RESOLVD) study showed that another AII receptor antagonist, candesartan, appears to be comparable with ...

It is one of two angiotensin II receptors, and its partner, AT1, has been successfully used as a target for high blood pressure medications. The information they uncovered could give drug developers a ...