Upon attachment to the bacterium, the bacteriophage pierces the host cell envelope and injects its ... Each protein is labeled with a unique color. The model contains more than 1.3 million atoms ...

The study may provide clues to how similar viruses infect cells and suggest ways for developing a new class of antibiotics and other drugs to prevent illnesses caused by viral pathogens. Scientists at ...

This study reveals the potential of engineered phage-IL-12 therapy in melanoma, enhancing immune response and tumor ...

Rather than attacking typical plant or animal cells, the bacteriophage uses ... 4” /> * The lead photo is technically a nano-scale model of a T4 bacteriophage. The gallery has real shots.

AlphaFold2 model of the hinge connector of the distal tail fiber (b). The mutation of a Threonine to an Arginine is indicated (position 94). Alpha helices are indicated in red and beta sheets in ...

Dokland’s study, “Structure of the host cell recognition and penetration machinery of a Staphylococcus aureus bacteriophage,” was recently published in PLOS Pathogens. The first author on the paper ...

Using advanced technologies to explore the inner workings of bacteria, biologists have provided the first example of cargo within bacteriophage cells transiting along treadmill-like structures.

To investigate the downstream effects of phage consumption by mammalian cells, Barr and his team applied highly purified T4 phage, a well studied bacteriophage that infects Escherichia coli, across ...

Picoviruses always kill the cells they infect, after binding to the bacterial cell wall, enzymatically breaking through that wall, penetrating the cell membrane and injecting viral DNA into the cell.