The cellular sensors have long been presumed to be located in a certain type of cell in the kidney, but have only ... the goldilocks zone the body has “baroreceptors” that sense blood pressure.

1 These negative-feedback neural loops regulate specific groups of both sympathetic neurons sending nerve impulses to the vasculature, the heart, and the kidney and parasympathetic neurons sending ...

Scientists have long suspected that these barometers, or "baroreceptors," existed in specialized kidney cells called renin cells, but no one has been able to locate the baroreceptors until now.

The efferents that are most crucial to BP control are tonically active at rest, and their defining property is a powerful feedback inhibition of arterial baroreceptor origin (barosensitive efferents).

Patients with chronic kidney disease (CKD ... progressed in an age-related fashion and correlated with the decline in baroreceptor afferent function. “Clinically, this is an important finding ...