bladder, pancreas, kidney, and nose. There are even some in the eye and brain. The results, published in a preprint on bioRxiv April 21, show that such cells are strikingly abundant. Many are ...

Specifically, the M3 receptor has an important role in bladder function. Nonselective antimuscarinics, such as oxybutynin, block not only M3 receptors in the lower urinary tract but also cardiac ...

Figure 2: Expression of transient receptor potential cation channel subfamily V member 1 (TRPV1) in urothelial cells of the rat urinary bladder. Although TRPV1-null mice are anatomically normal ...

Discover a study that investigated whether scheduled IV acetaminophen administration would offer longer-lasting relief for ...

The parasympathetic nerves, primarily cholinergic, stimulate detrusor contraction and sphincter relaxation, resulting in bladder emptying. During filling, sympathetic nerves release the ...

Bladder cancers (BCs) that invade the muscle layer are classified as muscle-invasive bladder cancers (MIBCs). The MIBC subtype accounts for around 25% of all BC cases, with a significant proportion of ...

1,2 Sunobinop is an investigational, novel and potential first-in-class oral compound designed to bind to and activate the nociceptin/orphanin-FQ peptide receptor (NOP), a protein that is widely ...

Diabetic cystopathy is a chronic complication of diabetes with a classic triad of symptoms: decreased bladder sensation, increased bladder capacity, and impaired detrusor contractility.