They can help treat cancer that has spread to the bones (bone metastasis), which is quite common. In many cases, they can be used as soon as bone metastases are diagnosed. These drugs not only ...

Zoledronic acid is a potent, new-generation bisphosphonate indicated for the treatment of documented bone metastasis in patients with solid tumors and bone lesions associated with multiple myeloma.

A key gene that fuels the molecular cascade driving prostate cancer bone metastasis progression may open avenues for targeted therapies. Laura is an assistant editor for The Scientist. She earned her ...

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The blood pressure was 150/80. The chalky appearance to the bones was interpreted as osteoblastic metastases. Seizures were controlled for the 1st few days with diphenylhydantoin and phenobarbital ...

Enzyme Inhibition Promotes Bone Formation and Curbs the Development of Bone Metastases Dec. 20, 2022 — In our bones, specialized cells called osteoblasts are responsible for building up bone ...

For example, if breast cancer spreads to the bone, the cancer cells in the bone are actually breast cancer cells. The disease is metastatic breast cancer, not bone cancer. Metastatic cancer falls ...

[20] The maximum recommended zoledronic acid dose for the treatment of bone metastases is 4 mg by IV infusion, infused over no less than 15 minutes. Preinfusion examinations include a physical ...