Innovative MRI-based Technique Date: December 15, 2008 Source: CNRS Summary: A new approach to the early prediction of the evolution of cerebral infarcts caused by stroke has just been evaluated ...

The penumbra is an area of brain tissue that is damaged but not yet dead after focal ischemia. The existence of a penumbra implies that therapeutic salvage is theoretically possible after stroke.

Surrounding the infarct core is a larger area of brain that is hypoperfused, but does not infarct rapidly due to blood flow from unaffected collateral vessels, and is termed the ischemic penumbra.

Patients presenting with cerebral infarct volumes of greater than 70-100 ml in the anterior circulation, ... while hypoperfused, but still-viable brain is called the penumbra.

Article: "Hypoxic preconditioning stimulates angiogenesis in ischemic penumbra after acute cerebral infarction " by Sijie Li1, Yanbo Zhang2, Guo Shao3, Mingfeng Yang2, Jingzhong Niu2, Guowei Lv1 ...

Brain damage that occurs even days after a stroke, ... waves of peri-infarct depolarization pound surrounding brain tissue, ... "The penumbra exists for several days, ...

A software designer says the Penumbra Coil 400, used to treat aneurysms, malfunctioned during surgery at Overlake Hospital in Bellevue and caused him to suffer brain damage.

This condition, which has been described as malignant middle-cerebral-artery infarction, is associated with 80% mortality due to herniation during the first week, despite maximal conservative ...