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Other studies suggest that glucose is not just used as a fuel to generate heat but also may have other important functions in keeping brown adipocytes active and healthy. We need to know that ...
Using positron-emission tomography (PET), we found that cold-induced glucose uptake was increased ... and protein levels of the brown-adipocyte marker, uncoupling protein 1 (UCP1).
8 As transgenic expression of UCP1 in muscle is known to increase insulin-mediated glucose uptake, 9 human skeletal muscle brown adipocytes might protect not only from obesity but also from ...
Conversely, beige and brown adipocytes are highly energy-expending ... ablation have secondary effects on body weight gain and glucose tolerance with aging," explains Prof. Schuele.
However, the adaptation wasn't enough to explain the blood sugar-lowering effect. Looking closer, the researchers found that the white adipocytes of animals that had extra PLIN5 in their brown ...
ugr.es Brown adipose tissue (BAT) has the ability to oxidise glucose and lipids, and dissipate energy in ... enriched mitochondria and express the brown adipocyte-specific UCP-1. A potential clinical ...
Adipocytes, also known as fat cells ... When the body is exposed to cold, glucose uptake is elevated in brown and beige fat cells, with glucose supplying the energy for thermogenesis.
The thinking behind this new study was to explore the way activation of brown fat may impact on tumor growth, which relies heavily on glucose. The experiments began with mouse models of various ...
Not only did the investigators find reduced fat mass in the NPR-C knockout mice, as compared with wild-type mice, but they also observed that genes characteristic of brown adipocytes were ...
Therapies that help lower blood glucose levels are gravely needed ... but while there are many similarities between brown and beige adipocytes, the two cell types originate from different ...
as well as elucidate the role of EPAC1 in the differentiation of brown adipocytes. Oxygen consumption and body composition of mice were analyzed at regular intervals. Glucose tolerance was ...
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