AA denotes amino acid, Bunya_RdRp bunyavirus RNA-dependent RNA polymerase, and CCHFV Crimean–Congo hemorrhagic fever virus. The M segment contained a single open reading frame encoding a 1436 ...

Vanderbilt University Medical Center has joined an extraordinary national effort to develop and stockpile new vaccines and ...

Here, we describe a broadly applicable strategy, based on llama-derived single-domain antibodies (VHHs), for the development of bunyavirus biotherapeutics. The method was validated using the zoonotic ...

The National Institutes of Health (NIH) has established a pandemic preparedness research network to conduct research on high-priority pathogens most likely to threaten human health with the goal of ...

The National Institutes of Health (NIH) has established a pandemic preparedness research network to conduct research on ...

The National Institutes of Health (NIH) has established a pandemic preparedness research network to conduct research on ...

The sandfly-transmitted viruses are all in the Bunyavirus group, the Phleboviruses; some 45 viruses are associated with sandflies globally. Some Phleboviruses are transmitted by mosquitoes, e.g. Rift ...

It is named after the area in western Uganda where it was first isolated. BUNV remains an important research model: it was the first bunyavirus whose genome was completely sequenced, and significantly ...

Most of the antiviral agents that have been approved, and are currently used in the treatment of virus infections, are targeted at HIV, HBV, herpes simplex virus (HSV), varicella-zoster virus (VZV ...

Despite impressive therapeutic progresses in the battle against infections, microorganisms are still a threat to mankind. With hundreds of antibacterial molecules, major concerns remain about the ...