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Scientists propose CDK2 enzyme as new target for cancer therapyMore information: Vishnu Kumarasamy et al, Discrete vulnerability to pharmacological CDK2 inhibition is governed by heterogeneity of the cancer cell cycle, Nature Communications (2025). DOI: 10. ...
We have cloned the gene encoding p33cdk2 and showed that it shares significant homology with p34cdk2, a protein kinase that regulates cell-cycle progression in all eukaryotic organisms. In addition, ...
This was accompanied by downregulation of key cell cycle proteins such as CDK2, Cyclin A2, CDK4/6, and Cyclin D1/E1 complexes. Additionally, ferulic acid upregulated tumor suppressor proteins p53 ...
This was accompanied by downregulation of key cell cycle proteins such as CDK2, Cyclin A2, CDK4/6, and Cyclin D1/E1 complexes. Additionally, ferulic acid upregulated tumor suppressor proteins p53 ...
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