Purpose: A summary of the basic science underlying the current controversies regarding cyclooxygenase-2 (COX-2)-selective nonsteroidal antiinflammatory drugs (NSAIDs), including data on their ...

Meloxicam is an enolcarboxamide with preferential COX-2 inhibitory activity. In vitro studies with human tissues have confirmed the high affinity of meloxicam for COX-2, whereas COX-1 was ...

COX-2 is involved in prostaglandin synthesis and expressed throughout the nervous system, where it participates in pain sensitivity and in synaptic plasticity. Microsomal prostaglandin E synthase ...

Medically reviewed by David Ozeri, MD Prescription anti-inflammatory medications are used to reduce pain, inflammation, and ...

NSAIDs are among the most common pain relievers in the world. And lately, they're among the most controversial. Find out what these anti-inflammatory pills actually do inside your body. NSAIDs ...

A concerning number of newly diagnosed patients discontinue their medication within a year. Nearly 40% of patients diagnosed ...

Nearly 40% of patients diagnosed with type 2 diabetes imperil their health by stopping their medication within the first year, diabetes experts warn.