In bacteria, the viral invaders are called bacteriophages ... catalog hundreds of thousands of new DNA memories that the CRISPR Cas9 system had created from the test phages, honing in on those ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas ... Genome engineering in bacteria remains a complex multistep process. Here, the authors developed make-or-break Prime Editing, a precise ...

A Kobe University team was able to edit the DNA of Lactobacillus strains directly without a template from other organisms.

Latest study leverages new constructs for nuclear localization signal (NLS) sequences to improve editing efficiency in human ...

It is based on a simplified version of the bacterial CRISPR-Cas9 antiviral defence system. The development of the technique earned biochemists Emmanuelle Charpentier (one of the founders of ERS ...

Researchers have developed a machine learning model that predicts Cas9 proteins that can be tailored with designer properties for therapeutic use.

A Kobe University team was able to edit the DNA of Lactobacillus strains directly without a template from other organisms.

Genome engineering in bacteria remains a complex multistep ... The flexibility of CRISPR/Cas9 editing is severely constrained by the requirement that the modification site is located in close ...

Given that microbes helped make Earth habitable, we could use synthetic biology to engineer microbes to speed up a similar ...

Genome editing has advanced at a rapid pace with promising results for treating genetic conditions-but there is always room for improvement.

Learn about Brink Therapeutics as it raises $4 million to go beyond CRISPR with engineered recombinases in CAR T therapy.

A team was able to edit the DNA of Lactobacillus strains directly without a template from other organisms. This technique is indistinguishable from natural variation and enabled the researchers to ...