A new gene editor takes advantage of CRISPR-associated proteins to insert whole genes into the genome, scientists report.

At the upcoming annual meeting of the American Society of Gene and Cell Therapy, scientists from Huidagene Therapeutics will share an update on the development of their CRISPR-high-fidelity ... HG302 ...

Since the bacterial-origin CRISPR-Cas system rose to popularity as a genome editing tool, scientists have wondered whether other genome editors exist in nature. Now, two independent research teams ...

The University of Bayreuth's Biomaterials research group has, for the first time, successfully applied the CRISPR-Cas9 ...

In gene and cell therapy, RNP-mediated CRISPR gene editing is quickly emerging as the new norm. For many gene editing firms, GenScript has created hundreds of Cas9, Cas12a, Cas13a, MAD7 ...

CRISPR-Cas holds great promise ... 13ds also showed similar levels of protein in the cells. The team then tried miniaturizing Cas13b using AlphaFold2 and their IDC strategy, and created two mini ...

The interaction between RNA-binding proteins (RBPs) and circular RNAs (circRNAs) has emerged as a key area of interest in understanding cancer biology.

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

Under the terms of the arrangement, EditCo will incorporate Promega’s bioluminescent and protein-labeling technologies into its CRISPR-engineered cell lines. According to the partners ...

In 2014, CRISPR and CRISPR-associated (Cas) proteins were still primarily research ... with funding levels dropping to $12.6 ...

Cas10 relieves host growth arrest to facilitate spacer retention during type III-A CRISPR-Cas immunity. Cell Host & Microbe 32(12), 2050-2062 ... safeguards the import of mitochondrial membrane ...