Total duration of antibiotic therapy in adults hospitalized with sepsis was significantly shorter among those who received PCT-guided care vs standard care.

Measurements and Main Results: Serum procalcitonin and C-reactive protein were measured at admission in all patients and, when possible, repeated 6, 12, 24, and 48 hrs later. In most cases ...

Anyone can develop an inflammation but in some people it may be silent Therefore getting proper tests can help confirm your ...

The most common biomarkers investigated to predict mortality are procalcitonin, C-reactive protein (CRP), pro-adrenomedullin, inflammatory cytokines and D-dimer. Despite the interest of all these ...

For critically ill patients on antibiotics for suspected sepsis, monitoring one biomarker safely shortened the course of these medications in the ADAPT-Sepsis randomized trial. Daily assessment of ...

For biomarkers involved in the trial, levels of PCT and CRP are known to be associated with infection and inflammation. Used as a form of status update, biomarker levels can guide when to stop ...

and colleagues assessed whether decisions based on assessment of C-reactive protein (CRP) or PCT safely results in a reduction in the duration of antibiotic therapy. The analysis included 2,760 ...