Explore how biological sex influences healing in tissue engineering. Discover novel insights from recent bone research ...

Cartilage of articular joints grows and matures ... increases in either the cell volume fraction by proliferation or hypertrophy or in the matrix volume fraction by a net accretion of constituent ...

By modeling cartilage-to-bone transition with innovative callus organoids, scientists discovered two distinct pathways—hypertrophic cartilage and fibrocartilage—driven by early progenitor cell ...

The study revealed striking differences between male and female-derived organoids in terms of cartilage formation. Male-derived organoids predominantly produced hypertrophic cartilage (HyC ...