Cataplexy is a type of sudden weakness in your muscles that can make you go limp or temporarily lose your ability to move. Here’s what you need to know about the symptoms, causes, and treatments.

Orexins are chemicals in your brain that help your body stay awake. When you have narcolepsy, you don’t have enough neurons that make orexins.

Cataplexy is a condition that can range from barely noticeable muscle weakness to a complete blackout. Learn more about this sudden loss of voluntary muscle tone when strong emotions are ...

SAN DIEGO -- AXS-12 (reboxetine), an investigational treatment for narcolepsy, reduced weekly cataplexy attacks and in some cases provided complete remission, the phase III SYMPHONY study showed.

AXS-12, known as reboxetine back when it was available as an antidepressant in the United States, may decrease cataplexy attacks in narcolepsy, a phase 3 trial suggests.

A recent paper describes six cases where cataplexy was initially diagnosed, but in all cases the weakness spells were eventually not attributed to cataplexy.

In a phase 2 trial involving patients with narcolepsy type 1, an orexin receptor 2 agonist resulted in greater improvements on measures of sleepiness and cataplexy than placebo over a period of 8 ...

Imagine repeatedly falling asleep or falling down paralyzed when laughing or startled. This is life with narcolepsy, which can be triggered by an infection or the flu.

Cataplexy is a sudden temporary loss of muscle tone in the body, which occurs during times of intense emotional states like laughter or anger. Such muscle weakness can cause: head nodding ...

Common narcolepsy symptoms include sleep attacks, cataplexy, sleep paralysis, and hallucinations. Even though the symptoms can greatly affect our daily routines, they often go unidentified — and ...

Narcolepsy may stem from the lack of the neurotransmitter hypocretin. It is a long-term neurological condition that causes fragmented sleep, daytime sleepiness, brain fog, and other symptoms.