New migraine treatments have brought stunning relief to many people by blocking the action of calcitonin gene-related peptide (CGRP), a protein in the brain involved in the migraine process.

Research reveals howneurogenic connection can directly trigger inflammatory processes, creating pain patterns that challenge ...

Study uncovers new insights into pain pathways associated with temporomandibular joint (TMJ) disorders. Using an innovative in vivo imaging tool to capture functional activity in mouse models of TMJ ...

Discover the latest breakthroughs in migraine treatment for 2025, including CGRP inhibitors, AI-powered personalized plans, ...

In the spinal cord, these changes include increases in calcitonin gene-related peptide (CGRP) and dynorphin, peptides that contribute to the maintenance of pain. All these alterations, except for ...

Atogepant vs placebo for the preventative treatment of migraine alleviated migraine symptoms across 3 clinical trials on day 1.

After establishing this connection, tumors signaled the sensory nerves to release the peptide Calcitonin Gene Related Peptide (CGRP), inducing electrical signals in the tumor. Though the cancer ...