The challenge of internalizing impermeable molecules into cells persists in drug development, particularly concerning ...

Most nucleic acid extraction kits use spin-column technology, where DNA or RNA binds to a silica-based membrane in the presence of high concentrations of chaotropic salts, such as guanidine ...

Chaotropic solutes are a diverse group of substances that can disrupt the non-covalent interactions and hydrophobic forces that hold macromolecules together. Conversely, kosmotropic substances ...