Enterotoxins (cholera toxin [CT] or STb), which selectively ... Disorganization of the actin cytoskeleton induces alterations of intestinal barrier functions, leading to passage of fluids into ...

Cholera is caused by ingesting a bacteria known as Vibrio cholerae. It's found in contaminated water and food, explains Ivers, which then produces a toxin in the small intestine that leads to the ...

A person with CF cannot contract cholera, because the toxin cannot open the chloride channels in the small intestine. Carriers of CF enjoy the mixed blessing of a balanced polymorphism.

Experimental treatments such as CTB-KDEL, a modified cholera toxin B subunit that induces mild ER stress, have shown ...

Since 2022, Ethiopia has been grappling with a persistent cholera outbreak, with nearly 60,000 cases and 726 fatalities reported. The waterborne disease has now found its way to Europe after a few UK ...

Cholera bacteria releases a toxin inside the small intestine which causes the body to expel large amounts of fluid. Most people can survive cholera with prompt and adequate treatment. However, in ...

[9] The specific activity of ZOT on tight-junction regulation suggests that this toxin mimics a related physiological modulator of the intestinal epithelial barrier. Using immunopurification based ...