Cilia drive fluid flow in development and physiology, but this requires that all cilia in a tissue orient the same way. Earlier studies indicated that both planar cell polarity (PCP) signalling ...
Several components of the hedgehog (Hh) pathway are crucial to basal cell carcinoma (BCC) tumorigenesis. Primary cilia have emerged as key organelles in Hh signal transduction in mammalian systems ...
Motile cilia unify axonemal orientation (AO) through cytoskeleton-mediated swiveling of basal foot (BF) to drive directional fluid flow across epithelia. The authors show that BF and AO are ...
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