As disease severity increases, submucosal edema and injury can result in cobblestoning of the mucosa, which is seen more often in Crohn's disease than in ulcerative colitis. Patients with severe ...

INTRODUCTION Crohn’s disease (CD) involves the entire gastrointestinal tract ... We observed CD-specific oral lesions: diffuse asymptomatic buccal swelling in 12 patients (23%) and cobblestoning in 5 ...