After the onset of ischemic stroke, a volume of brain rapidly infarcts, termed the core, while hypoperfused, but still-viable brain is called the penumbra. Occlusion of a minor artery will result ...

In the infarct core, necrosis occurs within a few ... such as hypoxia in ischemic stroke. However in the penumbra, there are multiple cell death mechanisms that are activated: excitotoxicity ...

2 Progression over Time (Left to Right) of the Infarct Core (Red), with Irreversible Damage at the Expense of the Ischemic Penumbra (Green). Acute stroke is typically characterized by the sudden ...

The Stroke Treatment and Revascularization Therapy (START) trial, sponsored by Penumbra, Inc., is one of the first prospective, core-lab adjudicated, multicenter studies to show a correlation ...

However, this method is often imprecise, as stroke damage can affect scattered ... accurately calculates the core and penumbra areas of the brain, providing a comprehensive and precise assessment ...

Core-lab adjudicated mTICI 2b ... Results of an additional study evaluating Penumbra’s aspiration thrombectomy system for ischemic stroke revascularization using the ADAPT approach, the COMPASS ...

Some stroke statisticians believe that the cost ... hours can help preserve the aerobic pathway so that the infarct core and penumbra sizes are minimized, as shown by a statistically significant ...

US-based Penumbra has completed enrolment for the THUNDER Investigational Device Exemption study of its advanced thrombectomy technology for acute ischemic stroke treatment. This study will ...

., announces the launch of an educational website , designed to empower the public with the knowledge they need to help stop stroke. The website asks visitors to “Join the Quest” and learn ...