Our initial studies in pig models proved that either acute permanent occlusion or constriction of the coronary sinus enriches epicardial and intramyocardial blood vessels network (i.e ...

The adaptive response of the fetal heart ... in porcine coronary artery endothelial cells (20), newborn (23–25) and adult rabbit heart ventricles (26), and adult guinea pig ventricles (27 ...

REN-001 delivered locally via low-dose retrograde coronary sinus infusion demonstrated robust, diffuse cardiomyocyte transduction in a large animal heart Sign up for our newsletter to get the ...

The paper, titled, “Cardiac Transduction in Mini-Pigs After Low-Dose Retrograde Coronary Sinus Infusion of AAV9-BAG3: A Pilot Study,” was published in the peer-reviewed Journal ...