Stimulation of inhibitory interneurons leads to a reduction in the firing rates of cortical pyramidal neurons, cells that are critical for receiving and transmitting sensory information.

This experimental work is among the first of its kind on live human neurons and one of the largest studies of the diversity of human cortical pyramidal cells to date. Scientists at the Krembil ...

Neuroscientists can now make precise genetic tweaks to the neurons that are most affected by brain diseases such as Parkinson ...

beyond the fact that they "hang" individually among great crowds of excitatory cells in the cortex called pyramidal neurons, and that their relatively short branches make contact with these ...

Their cell bodies have a unique pyramidal shape that is the source of their name. They make up about two-thirds of all neurons in the cerebral cortex of mammals, making them important for many ...

The cortex consists of recurrent networks, where pyramidal cells send action potentials down their axons to excite interneurons, which in turn inhibit the pyramidal cells through disynaptic ...

But Guo et al show convincingly (with the help of genetically modified mice) that OPCs do become neurons in the piriform cortex of adult mice. Once they've been "born", these new neurons mature into ...

Most of the cortex is composed of excitatory cells called pyramidal neurons (PNs). The IOB team wanted to study when and how these neurons assemble into the first active circuits in the cortex ...

The findings gathered by Musall and his colleagues delineate the functionally different cortical activity patterns that different types of pyramidal cells in the mouse brain elicit during decision ...