In two such reactions, the Nobel Prize–winning Suzuki and Negishi cross couplings, a transition-metal ... more popular neighbors on the periodic table (Nat. Catal. 2019, DOI: 10.1038 ...

With the optimal conditions for highly selective alkyl–aryl cross-coupling determined, the scope of the reaction of alkyllithium reagents and arylbromides was examined (Table 2). Table 2 Scope ...

Using directed evolution, researchers have developed an enzyme that catalyses the formation of biaryl bonds (Nature 2022, DOI: 10.1038/s41586-021-04365-7). This new enzyme makes carbon-carbon ...

A new strategy for ligand design may enable challenging metal-catalyzed cross couplings reactions that are indispensable to drug development, according to a study published in Nature Chemistry.

Professor David Phillips, President of the Royal Society of Chemistry, said of the Nobel Prize for Chemistry announcement today: "The metal-based 'coupling' reactions pioneered by this year's three ...