Finally, the team compared the repression of their TALE dimer with LacI. The covalent TALE dimer performed comparably to LacI based on their modeling. “That was really where it became intriguing that ...

Covalent selection identified lysine-targeting covalent inhibitors against phosphoglycerate mutase 1 (PGAM1), bromodomain (BRD) family proteins, and ubiquitin-conjugating enzyme E2 N (UBE2N ...

A covalent bond is a shared pair of electrons between two non-metal atoms, for example carbon dioxide. Figure caption, Two atoms sharing a pair of electrons. A covalent bond happens when the ...