One of the longstanding challenges in chemical biology has been finding ways to directly observe biological processes at work inside living cells without disturbing the action. In order to unlock new ...

The two chemical reactions probed here, imine hydrolysis and CuAAC, have been analysed to different depths. In the case of the imine hydrolysis, the kinetics is rather complex and the pH ...

The most popular of the click reactions, the copper(I)-catalyzed azide-alkyne cycloaddition, or CuAAC, is commonly used by chemical biologists, materials scientists, and polymer chemists.

The light irradiates the materials to photostimulate the two chemical reactions, but not simultaneously. First up is a reaction called the copper-catalyzed azide-alkyne cycloaddition (CuAAC ...

Copper-catalyzed azide-alkyne cycloaddition (CuAAC ... that’s a chemical biologist’s dream,” Prescher says. Every time a new click reaction happens, a whole new world opens up.

utilizes a copper-catalyzed azide-alkyne cycloaddition (CuAAC) reaction that makes it possible for certain chemical building blocks to "click" together in an irreversible linkage, analogous to the ...