We investigated whether sodium zirconium cyclosilicate (ZS-9), a novel selective cation exchanger, could lower serum potassium levels in patients with hyperkalemia. In this multicenter ...

Severe hyperkalemia (serum potassium level, ≥6 mmol per liter) can cause lethal cardiac arrhythmias and represents a medical emergency. Existing therapies do not remove excess potassium ...

Lokelma is a branded medication that contains sodium zirconium cyclosilicate. It isn’t currently available in generic form. It comes as a powder that you mix into water and then drink.

Discover comprehensive details about Sodium Zirconium Cyclosilicate, including its pronunciation, uses, dosage instructions, indications, and guidelines on how and when to take it or avoid it.

Effect of Sodium Zirconium Cyclosilicate on Potassium Lowering for 28 Days Among Outpatients With Hyperkalemia. JAMA , 2014; DOI: 10.1001/jama.2014.15688 Bradley S. Dixon.

Lokelma (sodium zirconium cyclosilicate) is a prescription drug used to treat high blood potassium levels. Lokelma can cause side effects that range from mild to serious. Examples include fluid ...

Evidence-based recommendations on sodium zirconium cyclosilicate (Lokelma) for treating hyperkalaemia in adults. The recommendations in this guidance represent the view of NICE, arrived at after ...

CHICAGO, IL — A polymer-based oral agent that sequesters potassium in the intestine, zirconium cyclosilicate, or ZS-9 (ZS Pharma), given to patients with hyperkalemia brought serum potassium ...

People living with persistent hyperkalaemia in England, Wales and Northern Ireland will now be able to access repeat prescriptions of sodium zirconium cyclosilicate (SZC) in the community. [1] This ...

where sodium zirconium cyclosilicate is currently under separate regulatory review Source text for Eikon: Further company coverage: The Trump administration lifted a month-old stop-work order on a ...

Am J Manag Care. 2015;21(11 suppl): S212-S220. 13. ClinicalTrials.Gov: A Study to Evaluate the Effect of Sodium Zirconium Cyclosilicate on Chronic Kidney Disease (CKD) Progression in Participants ...

The recommended starting dose of sodium zirconium cyclosilicate is 10 g, administered 3 times a day orally as a suspension in water. When normal serum potassium levels are reached, the maintenance ...