Often characterized by involuntary motor or vocal tics, Tourette syndrome typically appears in childhood and affects up to ...

A recent study published in Engineering delves into the complex mechanisms of drug addiction, highlighting the crucial role of astrocytic G ...

The study specifically examines two types of GPCRs expressed on astrocytes: dopamine D1 receptors (D1R) and metabotropic ...

Disruptions in the dynamic balance of D1-receptor mediated phosphorylation and dephosphorylation cascades in different regions of the neuron may lead to impaired integration of synaptic inputs.

Dopamine’s effects in the brain are mediated by postsynaptic D1 and D2 receptors. Adenosine A1 and A2A receptors are uniquely positioned to counteract the excessive stimulation of dopamine receptors ...