Their findings, published in Nature Neuroscience, suggest that different aspects of reward-related behavior are supported by two distinct dopamine receptors, namely D3 and D1. "The previous ...

To date, five different subtypes of dopamine receptors, termed D1 through D5, have been cloned and characterised (Missale et al. 1998). These five subtypes have been grouped into two different ...

Dopamine’s effects in the brain are mediated by postsynaptic D1 and D2 receptors. Adenosine A1 and A2A receptors are uniquely positioned to counteract the excessive stimulation of dopamine receptors ...

Receptors can display different ligand binding properties depending on whether or not they are engaged in a receptor heteromer. The D 1-D 2 receptor heteromer provides an example of changes in ...