Together, eukaryotic DNA and the histone proteins that hold it together ... this highly compacted DNA is then arranged into structures called chromosomes. Chromosomes take different shapes in ...

Each nucleosome is made of DNA wrapped around eight histone proteins that function ... are associated with each nucleosome to maintain the chromosome structure.

Chances are you've seen an illustration of DNA's double-helix structure and even pictures of the chromosomes that make up the human genome. But where and how does the famous double helix fit into ...

The histone, in turn, forms large loops. So the DNA is much, much longer than the chromosome it makes up. The DNA of one of a fruit fly's chromosomes, for example, would be 12 times longer than ...

Scientists at the Institute of Cancer Research in London and Linköping University in Sweden have discovered how cells prevent ...

Like natural chromosomes, artificial ones need centromeres to attach to mitotic spindles and separate sister chromatids during cell divisions. Centromeres are defined by the presence of a specialized ...

Epigenetic reprogramming holds promise for reversing aging, addressing cellular aging mechanisms and paving the way for ...

Chromosomes are the carriers of the genetic and epigenetic ... Intriguingly, several replisome components, such as subunits of the DNA helicase and DNA polymerases, exhibit histone chaperone activity ...

This course provides and overview of epigenetic mechanisms, including DNA methylation, histone modifications, chromosome structure, and nuclear organization. We will discuss how molecules help ...

So, it's very easy to see,” she said. To zoom in on changes in chromosome organization during meiosis, the researchers used nuclear membrane and DNA damage protein stains to track nuclear behavior.

More information: Reuben Franklin et al, Histone chaperones coupled to DNA replication and transcription control divergent chromatin elements to maintain cell fate, Genes & Development (2025). DOI ...