Plasmacytoid dendritic cells (pDC) primarily function as weak antigen-presenting cells (APC), but have also been shown to ...

Innate immune cells are white blood cells that mediate innate immunity and include basophils, dendritic cells ... exogenous pyruvate to support energy metabolism. A new study shows that these ...

Molecular metabolism 28, 1-13 (2019). Impact 7.4 N Jaiswal, S Agrawal, A Agrawal. High fructose-induced metabolic changes enhance inflammation in human dendritic cells. Clinical & Experimental ...

We discovered the potential of anti-CXCR4 to reprogram the immunologically "cold" microenvironment of liver cancer to an immunologically "hot" one because of its effects on dendritic cells and the ...

Cell death terminates normal cellular functions, including respiration, metabolism ... by the antigen-sampling receptor CLEC9A on dendritic cells. Targeting caspase-8/c-FLIPL heterodimer with ...

Over the past ten years, we have investigated the developmental origin and homeostasis of macrophages and the related cell types monocytes and dendritic cells ... macrophages may control tissue growth ...