Because DCP-001 cells are derived from a cancer cell type they express multiple tumor-associated antigens, but with a mature dendritic cell phenotype. These antigens have been shown to overlap ...
When in the gut, these "DN2" B cells interact with dendritic cells co-expressing the lupus autoantigens DNASE1L3 and C1q, adjacent to bacteria. The normal functions of DN2 B cells, DNASE1L3 and ...
Verywell Health on MSN1y
Monocytopenia Symptoms and Causes
Medically reviewed by Archana Sharma, DO Monocytopenia describes a low number of monocytes, a type of white blood cell.
Sensory experience affects the structure of these tree-like neurites, which, it is assumed, modifies neuronal function, yet the evidence is scarce, and the mechanisms are unknown. To study whether ...
Over the past ten years, we have investigated the developmental origin and homeostasis of macrophages and the related cell types monocytes and dendritic cells. These cells play a major role in diverse ...
either by facilitating dendritic cell-T cell interactions or by enhancing the co-stimulation of T cells that engage tumor cells. Human cells are powerful therapeutic agents. With an expanding array of ...
Background The immune suppression mechanisms in pancreatic ductal adenocarcinoma (PDAC) remain unknown, but preclinical ...