MAIA Biotechnology (MAIA) announced the publication of preclinical data for its lead proprietary telomere-targeting THIO dimer in the ...

MAIA Biotechnology Announces Publication of Peer-Reviewed Study Featuring Potency and Potential of Novel THIO Prodrug ...

A new structural blueprint paves the way for improved targeting of cancer cells, particularly those with BRCA1 and BRCA2 ...

Scientists at Scripps Research have now captured the first detailed images of the DNA repair protein, Pol-theta, in action, revealing the molecular processes responsible for a range of cancers.

In Topo VI, two Top6A subunits assemble into a symmetric complex (a dimer) that reversibly cleaves both strands of a substrate DNA molecule. Two Top6B subunits each associate with one subunit of ...

Structural comparison of TnpB with Cas12 enzymes with high sequence similarity to TnpB revealed that Cas12 enzymes recognize longer target DNA sequences than TnpB by either asymmetric dimer ...